16300 Sand Canyon Ave., Suite 410, Irvine, CA 92618

Send Us a Secure Message

Call Us:  (949)732-3530

From general medicine to heart disease to diabetes, you'll always get the care and attention you deserve - whether you're feeling ill now or want to keep from becoming ill later. Together, we'll help you become proactive, stay healthy, and enjoy life.              -The Providers of Comprehensive

Care Center of Irvine

Office Hours

Monday - Friday: 8:00-5:00pm.

Saturday: Closed

Sunday: Closed

Comprehensive Care Center of Irvine

16300 Sand Canyon Ave., Suite 410

Irvine, CA 92618

Phone: (949)732-3530

Fax: (949)732-3533

Our Commitment to You

Contact Us

  • The office will be CLOSED on Memorial Day, May 25. 2015. To reach the on-call doctor, call (949)732-3530. ​

Office News

  • Starting March 1, 2015 Dr. Siskind will no longer be participating with Commercial HMO plans. Those patients will be transferred to Dr. Amanda Binns who is in the same office, unless other arrangements are made. All Medicare and PPO patients that do not join the concierge program will be referred to Dr. Binns.
  • As of March 1, 2015 Dr. Andrew Siskind will be changing his practice. Ann of Concierge Choice Physicians will be able to answer most questions you have. (818)984-2166.

Meet Our Providers

The key to a long, healthy, active life is prevention. A few simple steps now can keep a treatable condition from developing into a major health problem later. 

With the advanced, compassionate care at Comprehensive Care Center of Irvine,  you'll have a true partner in ongoing health. Our warm and friendly team is dedicated to providing high-quality medical care with a special focus on prevention.

Our Services

We accept Medicare, HMO plans with Greater Newport Physicians, most PPO

plans. We are on many CoveredCA plans. Please check with your carrier.

Health Insurance

New Patients

Please fill out our New Patient Forms prior to your appointment time.  


We typically have same-day and next-day appointment availability.

Call (949)732-3530 to schedule.

Appointment Request